Doris Berchtold’s paper online

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Doris Berchtold‘s systems-level study on molecular regulators of 6 membraneless organelles in human cells is now online. Check it out here.

Paper accepted in Molecular Cell

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Doris Berchtold‘s paper entitled ‘A systems-level study reveals regulators of membrane-less organelles in human cells’ is accepted for publication. Congratulations!! This work performed parallel large-scale gene perturbation screens in human cells on 6 membraneless organelles, and applied advanced computer vision and multivariate analyses to quantify effects on the morphology and abundance of these organelles at… Read more »

Paper accepted in Cell Systems

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Doris Popovic‘s paper entitled ‘Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells’ has been accepted for publication. Congratulations!! This work reports that correlations between mRNA and protein abundance of the same gene across thousands of single cells are often quite high, and that single cells that are outliers of such linear correlations are,… Read more »

Paper accepted in Science

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Gabriele‘s paper entitled ‘Multiplexed protein maps link subcellular organization to cellular states’ has been accepted for publication. Congratulations!! This work reports the development of iterative indirect immunofluoresence imaging (4i), which allows 40-plex immunostaining of hundreds of thousands of single cells using conventional primary and secondary antibodies in high-throughput. Combined with cellular computer vision, this generates… Read more »

Paper accepted in Nature

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Arpan‘s paper entitled ‘Kinase-controlled phase transition of membrane-less organelles in mitosis’ has been accepted for publication. Congratulations!! This work shows that the dual-specificity kinase DYRK3 drives the dissolution of membrane-less organelles as cells undergo cell division, and adds to our increasing evidence that DYRK kinases represent a novel class of cellular regulators that control liquid… Read more »