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Check out the beautiful cover on the June 5 issue of Cell, which is an artistic impression of regulatory genetic interactions in endocytic membrane trafficking, made by Lavinia Liberali and Luca Pitoni. It accompanies the Resource Article entitled:

A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking. Liberali P, Snijder B, Pelkmans L. Cell 157, 1473-1487, June 5, 2014 [Journal] [PDF] [PubMed]

CELL_157_6.c1.indd

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Prisca‘s paper entitled ‘A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking’ has been accepted for publication in Cell. Congratulations!!

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On January 1, Doris Berchtold joined our lab as a postdoctoral fellow funded by a HFSP fellowship. Doris did her PhD in the laboratory of Tobias Walther at the Max Planck Institute of Biochemistry in Martinsried, Germany. In her PhD work, she discovered a homeostasis mechanism by which cells respond to plasma membrane stress with compensatory changes in lipid synthesis. For more details, check here.

In our lab, Doris will apply her expertise in molecular cell biology to the poorly understood process of subcellular compartmentalisation through liquid phase transitions.

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The following 2 papers from the PelkmansLab are now online:

Battich N*, Stoeger T*, Pelkmans L. Image-based transcriptomics in thousands of single human cells at single-molecule resolution. Nat Methods. 2013 doi: 10.1038/nmeth.2657. Epub 2013 Oct 06. *Contributed equally [Journal]

Snijder B, Liberali P, Frechin M, Stoeger T, Pelkmans L. Predicting functional gene interactions with the hierarchical interaction score. Nat Methods. 2013 doi: 10.1038/nmeth.2655. Epub 2013 Oct 06. [Journal]

 

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The work of Nico and Thomas on large-scale image-based in situ transcriptomics using single-molecule RNA FISH probes based on branched DNA has been accepted for publication in Nature Methods.

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The work of Berend on the Hierarchical Interaction Score, a novel statistic to infer functional interactions between genes from large-scale multivariate gene perturbation screens has been accepted for publication in Nature Methods.